Virology, vaccines & Emerging Diseases

Recombinant Viruses

A recombinant vaccine is a vaccine developed through recombinant DNA technology. Vaccine approaches to contagious diseases are widely applied and appreciated. Amongst them, vectors based on recombinant viruses have displayed great promise and play a crucial role in the instigation of new vaccinations. Many viruses have been examined for their ability to express proteins from foreign pathogens and induce specific immunological responses against these antigens in vivo. Generally, gene-based vaccines can trigger potent humoral and cellular immune responses and viral vectors might be an effective strategy for both the delivery of antigen-encoding genes and the facilitation and enhancement of antigen presentation.

Recent methods in the diagnosis of viral infections:

• Immunoassay-based tests
• Amplification-based assays
• Next-generation sequencing
• Mass spectrometry