Immunology and Virology Diseases

Oncolytic Viruses

Viral oncology is a subsection of oncology that mainly deals with the treatment of human cancers /tumours with virus particles. Oncolytic viruses are viruses that preferentially target and kill cancer cells by replicate in cancer cells and thereby destroy cancer tissue without affecting healthy cells through a multi-modal mechanism of action. As Oncolytic viruses have a completely new mode of action, they are expected to lead to cancer regression or even cure in patients for whom current therapies have failed. These Oncolytic viruses have a triple mode of action i.e. cell lysis, systemic anti-cancer immune response, and local inflammation. Due to this triple mode of action, it can be combined with conventional tumour therapies.